Synergistic estrogenic effects of Fusarium and Alternaria mycotoxins in vitro
نویسندگان
چکیده
منابع مشابه
Emerging Fusarium and Alternaria Mycotoxins: Occurrence, Toxicity and Toxicokinetics
Emerging Fusarium and Alternaria mycotoxins gain more and more interest due to their frequent contamination of food and feed, although in vivo toxicity and toxicokinetic data are limited. Whereas the Fusarium mycotoxins beauvericin, moniliformin and enniatins particularly contaminate grain and grain-based products, Alternaria mycotoxins are also detected in fruits, vegetables and wines. Althoug...
متن کاملPlasma-Based Degradation of Mycotoxins Produced by Fusarium, Aspergillus and Alternaria Species
The efficacy of cold atmospheric pressure plasma (CAPP) with ambient air as working gas for the degradation of selected mycotoxins was studied. Deoxynivalenol, zearalenone, enniatins, fumonisin B1, and T2 toxin produced by Fusarium spp., sterigmatocystin produced by Aspergillus spp. and AAL toxin produced by Alternaria alternata were used. The kinetics of the decay of mycotoxins exposed to plas...
متن کاملFusarium Mycotoxins first
Despite intensive research, efforts to control Fusarium fungal infections and prevent or eliminate the presence of its mycotoxins in foods have not met with a great deal of success. Fusaria cause diseases, such as ear rot in corn and head blight and scab in wheat, that affect growth and yield of crops and were estimated to cause a loss of a billion dollars to wheat farmers in the USA in 1993. I...
متن کاملMolecular biology of Fusarium mycotoxins.
As the 20th century ended, Fusarium mycotoxicology entered the age of genomics. With complete genomes of Fusarium graminearum and F. verticillioides and several Fusarium gene expression sequence databases on hand, researchers worldwide are working at a rapid pace to identify mycotoxin biosynthetic and regulatory genes. Seven classes of mycotoxin biosynthetic genes or gene clusters have been ide...
متن کاملA sensitive zonagenetic assay for rapid in vitro assessment of estrogenic potency of xenobiotics and mycotoxins.
Mounting evidence confirms that hepatic biosynthetic processes are essential for female sexual maturation in fish, which is directly controlled by estrogens. These oogenetic events (zonagenesis and vitellogenesis) are induced in both sexes by estrogens. In this paper, we report the induction of zona radiata (zr) proteins and vitellogenin in primary hepatocytes from Atlantic salmon (Salmo salar ...
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ژورنال
عنوان ژورنال: Archives of Toxicology
سال: 2016
ISSN: 0340-5761,1432-0738
DOI: 10.1007/s00204-016-1795-7